ACTIVE RESEARCH
How can CRISPR-Cas9 be delivered to pancreatic beta cells?
LIVE
Research Events
Research Metrics
Confidence Score
78%
↑ 12% from baseline
Discoveries
23
+3 in last iteration
Resolution Rate
67%
↓ 5% from peak
Overall Progress
Open Challenges
AAV serotype selection for beta cells
Immune response mitigation
Payload size optimization
Off-target effects prevention
Terminal Output - challenge-tree-v2
$ thinktica agent run challenge-tree-v2
Starting challenge-driven research...
Connected to Neo4j at bolt://localhost:7687
Remote LLM: groq (llama-3.3-70b)
Processing iteration 4...
Quality score: 0.78
Challenges resolved: 1/4