It's essential to promptly address the issue reported by VirusTotal for the security and reliability of your application. The necessary actions will depend on the nature of the asset, your control over it, and the severity of the reported problem.

Consider the following steps:

* Investigate why the asset was flagged as malicious. Look into specific details, such as hosting malicious content, containing malware, spam involvement, or a history of cyberattacks.

* Isolate the asset from your primary systems if possible. Temporarily disabling or quarantining the asset can prevent potential further issues while conducting a thorough investigation.

* If you have control over the service associated with the asset, take immediate steps to patch and secure it. This may involve updating software, implementing stronger security measures, and ensuring it is not utilized for malicious purposes.